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The impact of smoking on lung cancer deaths is particularly striking.

Before the widespread use of cigarettes, lung cancer was a rare disease. In 1912, Adler published a book where he described all of the 374 verified cases of lung cancer from the worldwide published literature. Now, more than 157,000 deaths from cancer of the lung and bronchus per year are reported in the United States alone. In 2000, smoking caused 850,000 lung cancer deaths worldwide (71% of all lung cancer deaths).

Spiro SG, Silverstri GA. One hundred years of lung cancer. Am J Respir Crit Care Med. 2005; 172; 523-529.

Ezzati M, Lopez AD. Estimates of global mortality attributable to smoking in 2000. Lancet. 2003; 362: 847-852.

American Cancer Society. Cancer Facts and Figures 2010. Atlanta, GA: American Cancer Society. 2010. logo
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