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Some key links

Articles, books, reports, etc

Cochrane review : Combining behavioural support and medications increases chances of quitting smoking by 70-100%

Combining behavioural support and medications increases chances of quitting smoking by 70-100% Based on 40 studies which compare combinations of behavioural support and medications with groups receiving usual care or less behavioural support, the Cochrane review concludes that combined pharmacotherapy and behavioural support significantly increases smoking cessation.
Read here

Cochrane review : Adding behavioural support to medications increases quitting chances by 10-25%

Based on 38 studies which compare combinations of behavioural support and medications with groups receiving only medications, the Cochrane review concludes that adding 4 to 8 behavioural support sessions significantly but modestly increases smoking cessation.
Read here

An updated algorithm for choosing among smoking cessation treatments
by John Hughes

Read the abstract here. You can email John Huhes for the full article.

Read Jonathan Foulds' blog on

Alpert et al paper.
Nicotine patch safe but not effective in pregnancy, Coleman et al. paper in NEJM.

Read Richard Hurt's blog on

Alpert et al study.

Further critical analysis of Alpert et al. study

Read Hughes et al letter to Addiction.

The American Cancer Society has issued this reponse to Alpert et al. paper in Tobacco Control

We are not surprised at the results of this study, because evidence is accumulating that smokers who use NRT do not often use it as directed, nor do they use it long enough to stave off relapse, suggesting that we need to educate NRT users better (and the physicians and pharmacists who recommend it) and convince the FDA that 12 weeks is not long enough for NRT to be maximally effective.
We are a bit more surprised at the authors' conclusion (although it's an argument that has been around for years), ie. that "... increasing individual treatment coverage should not be at the expense of population evidence-based programs and policies". The tobacco control field needs to stop acting as if it is involved in a zero-sum game and, instead, advocate for comprehensive tobacco control approaches that include BOTH individual and population based approaches - the data are very clear that this is what works and that it is cost-effective. Our advocacy activities should reflect that and not pit one approach against another.

ATTUD response to Alpert et al. paper in Tobacco Control

Download here   -   voir l'article en français
ATTUD ( is very concerned that the recent study by Alpert et al. (2012), reports what we believe is a false conclusion that nicotine replacement therapies (NRTs) are not effective, and thereby discourages smokers from accessing the most commonly used scientifically-proven treatment option. There are several reasons we believe the conclusion is false...

Randomised controlled trial of cytisine in New England Journal of Medicine

Download abstract
Access NEJM website
Cytisine, a naturally occurring substance, triples a smoker's chances of stopping for at least a year, and could cost as little as $5-10 for a treatment course, potentially making tobacco dependence treatment affordable in low and middle income countries.

Clinical practice review on treating tobacco dependence

Access article
In the same issue of the New England Journal of Medicine, a clinical practice review on treating tobacco dependence in the healthcare setting is included. Michael Fiore & Timothy Baker wanted to provide you with a link to that manuscript.

A new era for treatment

Editorial on FCTC Article 14 guidelines by Martin Raw
In November 2010 the Conference of the Parties to the FCTC adopted guidelines for the implementation of Article 14. This editorial discusses the significance of the guidelines, which represent a new, global policy on tobacco dependence treatment.

Fallacies of anti-treatment proponents

Access article in English  -  Voir l'article en français  -
Acceso al artículo en español  -  是否應為吸煙者提供戒煙輔助
This Addiction Editorial from West et al. counters the fallacies to clear the way for a constructive debate on the role of cessation assistance in tobacco control.

Moore et al's 2009 BMJ NARS review on
Effectiveness and safety of nicotine replacement therapy assisted reduction to stop smoking: systematic review and meta-analysis

WHO MPOWER 2008 Global Tobacco Control Report
This report highlights the underdeveloped state of cessation support and treatment in the world, with only 5% of the world's population having access to a high level of service provision.

NRT recognized as Essential Medicine
Patch and gum have been placed on the WHO Model List of Essential Medicines.

45 country treatment survey
A survey of tobacco dependence treatment guidelines and treatment systems

Respiratory Health Effects of Passive Smoking: Lung Cancer and Other Disorders
US Environmental Protection Agency Publications. Office of Research and Development (ORD) report, (EPA/600/6-90/006 F), December 1992

Nicotine Addiction in Britain
A report of the Tobacco Advisory Group of the Royal College of Physicians

Setting the Record Straight: Secondhand Smoke is a Preventable Health Risk
Publication by the US Environmental Protection Agency. June 1994.

Fact Sheet: Respiratory Health Effects of Passive Smoking
Publication by the US Environmental Protection Agency, Office of Research and Development, Office of Air and Radiation. January 1993

Smoking and pregnancy: research findings from the Smokefree families program
Tobacco Control Supplement, September 2000 (Volume 9, Supplement 3). Contains several original articles and Smoke free families project briefs on smoking and pregnancy

Making Your Workplace Smokefree - A Decision Maker's Guide
CDC resources related to setting up smoke-free workplaces

Clearing the Air: How to Quit Smoking...and Quit for Keeps
National Cancer Institute, Cancer Control and Population Sciences

The voice of doctors
British Medical Association policy statements on smoking

World Medical Association Statement on Health Hazards of Tobacco Products
Adopted by the 40th World Medical Assembly, Vienna, Austria, September 1988 and amended by the 49th WMA General Assembly, Hamburg, Germany, November 1997

Turning the tide on the tobacco epidemic
Speech by Commissioner David Byrne WHO European Ministerial Conference for a Tobacco free Europe. Warsaw, 19 February 2002. (Available in English, French and German)

Children and Secondhand Smoke
Publication by the U.S. Environmental Protection Agency. Office of Air and Radiation (6604J). March 1999

Here's How You Can Help Your Pregnant Patients Quit Smoking
A leaflet for prenatal care providers provided by Smokefree Families, a program of the Robert Wood Johnson Foundation

The National Partnership to Help Pregnant Smokers Quit. Action Plan
A publication by a group of organizations that have joined forces to help pregnant smokers quit smoking. May 2002

NICE review on NRT and bupropion
Guidance on the use of nicotine replacement therapy (NRT) and bupropion for smoking cessation - full guidance (pdf) - NICE, March 2002

Combating the Tobacco Epidemic
World Health Report, 1999. Chapter 5

Clinical Practice Guideline to Promote Tobacco Use Cessation in the Primary Care Setting
Veterans Health Administration/Department of Defense, May 1999

Reports from the WHO European ministerial conference for a tobacco-free Europe:
The Warsaw Declaration for a Tobacco-free Europe
WHO European report on tobacco control policy
The tobacco control database

WHO Evidence Based Recommendations on the Treatment of Tobacco Dependence
These recommendations on treatment of tobacco dependence were commissioned by the World Health Organization and have drawn on the experience of a number of European countries

Treating Tobacco Use and Dependence
A how-to packet for implementing the US Public Health Service Clinical Practice Guideline logo
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